
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube.
Listen to this e…
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube.
Longevity by Design is a podcast for individuals looking to experience a longer, healthier life. In each episode, Dr. Gil Blander joins a co-host and an industry expert to explore a personalized health journey. The show helps you access science-backed information, unpack complicated concepts, learn what’s on the cutting edge of longevity research and the scientists behind them. Tune into Longevity by Design and see how to add years onto your life...and life onto your years.
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube.
Listen to this e…
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube.
Dr. Gil Blander and Ashley Reaver dive into the science behind GLP-1 agonists, a class of drugs originally developed for type 2 Diabetes but now widely used for weight management and longevity. They e…
Dr. Gil Blander and …
Dr. Gil Blander and Ashley Reaver dive into the science behind GLP-1 agonists, a class of drugs originally developed for type 2 diabetes but now widely used for weight management and longevity. They explore how these medications work, their effects on appetite, metabolism, and inflammation, and why they might be a game-changer for cardiovascular health, brain function, and fertility. While promising, they emphasize the importance of long-term research and consulting with medical professionals before considering these treatments.The conversation shifts to the role of wearables in health trackin…
If you're serious about building a healthy routine, you need to know how to build a habit loop. A habit loop is a habit-building framework that captures decades of behavioral research in three steps:…
If you're serious ab…
If you're serious about building a healthy routine, you need to know how to build a habit loop. A habit loop is a habit-building framework that captures decades of behavioral research in three steps:
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube.
Listen to this e…
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube.
In this episode of Longevity by Design, host Dr. Gil Blander welcomes Dr. Gabrielle Lyon, a board-certified family physician and New York Times bestselling author of Forever Strong. Gabrielle discusse…
In this episode of L…
In this episode of Longevity by Design, host Dr. Gil Blander welcomes Dr. Gabrielle Lyon, a board-certified family physician and New York Times bestselling author of Forever Strong. Gabrielle discusses the growing epidemic of sarcopenia, the loss of muscle mass and strength, accelerated by the use of GLP-1 medications. She emphasizes the importance of muscle health for overall longevity and introduces the concept of "muscle span."Gil and Gabrielle explore the critical role of skeletal muscle as a metabolically active organ, its impact on longevity, and the best ways to build and maintain muscl…
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube.
Listen to this e…
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube.
On this episode of Longevity by Design, Dr. Gil Blander speaks with Dr. Michael Ringel, COO of Life Biosciences, about the science of Aging and longevity. Michael discusses how evolution influences li…
On this episode of L…
On this episode of Longevity by Design, Dr. Gil Blander speaks with Dr. Michael Ringel, COO of Life Biosciences, about the science of aging and longevity. Michael discusses how evolution influences lifespan and why aging occurs. He explains the trade-off between resource allocation for reproduction versus maintenance and repair within the body. Caloric restriction and its effects on lifespan are explored through an evolutionary lens.Michael highlights the challenges and breakthroughs in longevity research. He touches upon the role of genetics and pharmaceuticals in manipulating lifespan and he…
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube.
Listen to this e…
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube.
In this episode of Longevity by Design, Dr. Gil Blander sits down with Dr. Jay Olshansky, a leading professor at the University of Illinois Chicago and a renowned expert in aging and biodemography. To…
In this episode of L…
In this episode of Longevity by Design, Dr. Gil Blander sits down with Dr. Jay Olshansky, a leading professor at the University of Illinois Chicago and a renowned expert in aging and biodemography. Together, they delve into the science of longevity, exploring how public health advancements in the 20th century revolutionized life expectancy and what lies ahead in the quest to extend both lifespan and healthspan.Dr. Olshansky unpacks the biological limits of human longevity, shedding light on why life expectancy gains are slowing despite medical advancements. He explains the interplay between ge…
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube.
Listen to this e…
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube.
Can personalized medicine unlock the secrets to living longer and healthier lives? In this episode of Longevity by Design, host Dr. Gil Blander sits down with Dr. David Barzilai, a renowned longevity …
Can personalized med…
Can personalized medicine unlock the secrets to living longer and healthier lives? In this episode of Longevity by Design, host Dr. Gil Blander sits down with Dr. David Barzilai, a renowned longevity physician and founder of Barzilai Longevity Consulting, to explore the science of extending healthspan through precision and Innovation.Dr. Barzilai shares his journey into biogerontology and longevity science, unpacking key concepts like the hallmarks of aging, the potential of Lifestyle interventions, and the translation of findings from animal models to human health. He highlights how evidence-…
If you’re an InsideTracker member—or you’ve been reading about the platform—you’re probably familiar with Healthspan Categories.These are the 10 categories that tell the full story of your h…
If you’re an Insid…
If you’re an InsideTracker member—or you’ve been reading about the platform—you’re probably familiar with Healthspan Categories.These are the 10 categories that tell the full story of your health:
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube.
Listen to this e…
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube.
On this episode of Longevity by Design, Dr. Gil Blander hosts Dr. Dmitriy Richard Starson, Founder and CEO of Passio, an AI-powered nutrition Coaching platform. Dmitriy discusses his career path from …
On this episode of L…
On this episode of Longevity by Design, Dr. Gil Blander hosts Dr. Dmitriy Richard Starson, Founder and CEO of Passio, an AI-powered nutrition coaching platform. Dmitriy discusses his career path from astrophysics to the world of nutrition tracking. He explains how his company seeks to make Healthy Eating more accessible. Passio aims to achieve this through user-friendly Technology like food scanning, voice logging, and personalized AI coaching.Dmitriy believes this technology will revolutionize how people approach nutrition. He envisions a future where food tracking is as commonplace as step t…
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube.
Listen to this e…
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube.
In this episode of Longevity by Design, our host Dr. Gil Blander welcomes Dr. Aubrey de Grey, a biomedical gerontologist, to explore the frontiers of aging research and lifespan extension. Dr. de Grey…
In this episode of L…
In this episode of Longevity by Design, our host Dr. Gil Blander welcomes Dr. Aubrey de Grey, a biomedical gerontologist, to explore the frontiers of aging research and lifespan extension. Dr. de Grey shares his work identifying and addressing the seven major categories of aging-related diseases. He discusses how targeted damage repair offers a promising alternative to traditional methods to slow aging, providing a path to longer, healthier lives.The conversation delves into the hallmarks of aging, their implications for medical research, and the challenges of translating results from animal m…
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube.
Listen to this e…
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube.
On this episode of Longevity by Design, Dr. Gil Blander welcomes Dr. John Erdman to discuss prostate Cancer and the impact of Diet on disease progression. John shares his personal connection to this d…
On this episode of L…
On this episode of Longevity by Design, Dr. Gil Blander welcomes Dr. John Erdman to discuss prostate cancer and the impact of diet on disease progression. John shares his personal connection to this disease and why he’s dedicated his research to understanding dietary interventions.John explains that prostate cancer is often slow-growing, with most men experiencing decades between early mutations and noticeable tumor Growth. He stresses the importance of early detection through regular checkups, including digital exams and PSA tests. While the medical community debates the effectiveness of th…
The holidays can be amazing, but tough. On the one hand, there’s pie and presents. But on the other, your routine is completely upended and you may find yourself straining under the weight of…
The holidays c…
The holidays can be amazing, but tough. On the one hand, there’s pie and presents. But on the other, your routine is completely upended and you may find yourself straining under the weight of obligations and responsibilities. A survey from the American Heart Association found that roughly two-thirds of people struggle to eat well or Exercise during the holiday season. And more than half fall behind on Sleep.1It makes sense. The short, cold days of winter make it hard to get outside. The endless supply of sweets can put you on a sugar roller-coaster. And you might be facing Stress or …
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube.
Listen to this e…
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube.
In this episode of Longevity by Design, Dr. Gil Blander welcomes Dr. Jens Juul Holst, a renowned Danish physician and physiologist, to discuss GLP-1, a hormone transforming our understanding of metabo…
In this episode of L…
In this episode of Longevity by Design, Dr. Gil Blander welcomes Dr. Jens Juul Holst, a renowned Danish physician and physiologist, to discuss GLP-1, a hormone transforming our understanding of metabolic health. Dr. Holst, who discovered and described GLP-1, explains its role as a gut-derived hormone that regulates appetite, insulin secretion, and digestion, offering a groundbreaking approach to managing obesity and type 2 diabetes.The conversation explores how GLP-1 receptor agonists, have evolved into powerful medications. These drugs help patients achieve significant weight loss, reverse di…
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube.
Listen to this e…
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube.
Episode highlights:Introduction: 00:00:00Why have you decided to become a scientist: 00:02:30What is fermentation: 00:07:45What microbes are involved in fermentation: 00:08:40How those microbes get in…
Episode highlights:I…
Episode highlights:Introduction: 00:00:00Why have you decided to become a scientist: 00:02:30What is fermentation: 00:07:45What microbes are involved in fermentation: 00:08:40How those microbes get into the fermented food: 00:09:35When the Humankind started to utilize fermentation: 00:11:20What is the difference between Probiotics and Live Cultures: 00:15:15What are the benefits of fermented food consumption: 00:17:43What foods are produced through lactic acid fermentation, and what are the best methods for making them at home: 00:23:10What is the positive effect of fermented foods on inflamma…
You probably know that recovery is an important aspect of fitness. It makes sense: If you bounce back fast from workouts, you’ll build more muscle and run faster. What’s harder to understand is r…
You probably know th…
You probably know that recovery is an important aspect of fitness. It makes sense: If you bounce back fast from workouts, you’ll build more muscle and run faster. What’s harder to understand is recovery’s role in overall health. As it turns out, recovery isn’t just about athletic performance. It also supports immunity, metabolism, and cardiovascular health.If you can improve your recovery, you’ll be more energized and less prone to soreness and injury. As a result, you’ll find it easier to keep your body in motion. You’ll be more likely to make it to the gym before work, hit you…
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube.
Listen to this e…
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube.
On this episode of Longevity by Design, Dr. Gil Blander welcomes Dr. Yanina Pepino, Professor of Ingestive Behavior at the University of Illinois, to discuss the fascinating link between taste, person…
On this episode of L…
On this episode of Longevity by Design, Dr. Gil Blander welcomes Dr. Yanina Pepino, Professor of Ingestive Behavior at the University of Illinois, to discuss the fascinating link between taste, personal preferences, and long-term health. Yanina's research shows our food environment significantly shapes cravings. This exposure starts as early as the womb, impacting future preferences.Yanina explains that bariatric surgery and GLP-1 medications are powerful tools for weight management. However, she emphasizes the importance of using these interventions as opportunities to adopt healthier ea…
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube
Listen to this episo…
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube
In this special "Ask Me Anything" episode of the Longevity by Design podcast, Ashley Reaver and Dr. Gil Blander from InsideTracker delve into their latest innovation, the Nutrition Nutrition Deep Dive…
In this special "Ask…
In this special "Ask Me Anything" episode of the Longevity by Design podcast, Ashley Reaver and Dr. Gil Blander from InsideTracker delve into their latest innovation, the Nutrition Nutrition Deep Dive Solution. After years of research and development, they share the journey of creating a food recognition platform that helps users track their food intake in real time. The goal is to provide users with personalized recommendations for better health and nutrition based on their dietary habits.Dr. Blander explains the challenges that arose over nearly a decade of development, including the complex…
In this episode of Longevity by Design, our host Dr. Gil Blander speaks with Dr. David Sinclair, a professor of genetics at Harvard Medical School, about the science behind aging and how we can extend…
In this episode of L…
In this episode of Longevity by Design, our host Dr. Gil Blander speaks with Dr. David Sinclair, a professor of genetics at Harvard Medical School, about the science behind aging and how we can extend both lifespan and healthspan. Dr. Sinclair shares his groundbreaking research on the role of epigenetic changes in aging and the potential to reverse this process.He explains how lifestyle factors, such as diet and exercise, can greatly impact our longevity, and highlights the importance of regularly monitoring health markers like blood glucose and cholesterol. Dr. Sinclair emphasizes the power o…
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube.
Listen to this e…
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube.
In this episode of Longevity by Design, Dr. Gil Blander talks with Dr. Renee Deehan, Senior Vice President of Science and AI at InsideTracker. They explore the world of Artificial Intelligence and its…
In this episode of L…
In this episode of Longevity by Design, Dr. Gil Blander talks with Dr. Renee Deehan, Senior Vice President of Science and AI at InsideTracker. They explore the world of artificial intelligence and its applications in health and wellness.Renee explains the differences between AI, machine learning, and large language models (LLMs). She discusses how InsideTracker has developed a specialized LLM called Ask InsideTracker. This tool allows users to interact with a vast knowledge base of health and wellness information.The conversation delves into the potential future applications of AI in perso…
In this episode of Longevity by Design, Dr. Gil Blander talks with Dr. Renee Deehan, Senior Vice President of Science and AI at InsideTracker. They explore the world of artificial intelligence and its…
In this episode of L…
In this episode of Longevity by Design, Dr. Gil Blander talks with Dr. Renee Deehan, Senior Vice President of Science and AI at InsideTracker. They explore the world of artificial intelligence and its applications in health and wellness.Renee explains the differences between AI, machine learning, and large language models (LLMs). She discusses how InsideTracker has developed a specialized LLM called Ask InsideTracker. This tool allows users to interact with a vast knowledge base of health and wellness information.The conversation delves into the potential future applications of AI in personali…
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube.
Listen to this e…
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube.
On this episode of Longevity by Design, Ashley Reaver, MS, RD, CSSD, and Dr. Gil Blander, delve into the intricate world of the immune system and its impact on aging with Dr. David Furman, Associate P…
On this episode of L…
On this episode of Longevity by Design, Ashley Reaver, MS, RD, CSSD, and Dr. Gil Blander, delve into the intricate world of the immune system and its impact on aging with Dr. David Furman, Associate Professor at the Buck Institute for Research on Aging. David discusses his groundbreaking research on inflammaging— uncovering how chronic, low-grade inflammation can accelerate the aging process. Discover how David's team developed a new inflammatory age test, soon to be available from his company Edifice Health, that uses five key proteins to assess an individual's inflammatory state…
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube.
Listen to this e…
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube.
In this episode of Longevity by Design, our host Dr. Gil Blander welcomes Dr. Renee Deehan and Nimisha Schneider from InsideTracker to discuss the role of personalized health and the advancements made…
In this episode of L…
In this episode of Longevity by Design, our host Dr. Gil Blander welcomes Dr. Renee Deehan and Nimisha Schneider from InsideTracker to discuss the role of personalized health and the advancements made through data science and artificial intelligence. Dr. Deehan elaborates on her background in molecular biology and how she transitioned to computational biology, emphasizing the importance of integrating large-scale biological data to develop high-resolution molecular models of diseases.Nimisha Schneider shares her journey from basic immunology research to computational biology, highlighting the …
In this episode of Longevity by Design, our host Dr. Gil Blander welcomes Dr. Renee Deehan and Nimisha Schneider from InsideTracker to discuss the role of personalized health and the advancements made…
In this episode of L…
In this episode of Longevity by Design, our host Dr. Gil Blander welcomes Dr. Renee Deehan and Nimisha Schneider from InsideTracker to discuss the role of personalized health and the advancements made through data science and artificial intelligence. Dr. Deehan elaborates on her background in molecular biology and how she transitioned to computational biology, emphasizing the importance of integrating large-scale biological data to develop high-resolution molecular models of diseases.Nimisha Schneider shares her journey from basic immunology research to computational biology, highlighting th…
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube.
Listen to this e…
Listen to this episode of Longevity by Design on Apple Podcasts, Spotify, and YouTube.
In this episode of Longevity by Design, hosts Ashley Reaver and Dr. Gil Blander welcome Dr. Julie Andersen, a distinguished neuroscientist at the Buck Institute for Research on Aging, who discusses he…
In this episode of L…
In this episode of Longevity by Design, hosts Ashley Reaver and Dr. Gil Blander welcome Dr. Julie Andersen, a distinguished neuroscientist at the Buck Institute for Research on Aging, who discusses her groundbreaking work on neurodegenerative diseases, focusing on Parkinson's and Alzheimer's. She explains how the field of geroscience is transforming our understanding of aging, revealing that common underlying processes in various diseases could lead to universal therapeutic approaches.Dr. Andersen dives into the gut-brain connection, highlighting how gut health significantly impacts brain ag…
In this episode of Longevity by Design, hosts Ashley Reaver and Dr. Gil Blander welcome Dr. Julie Andersen, a distinguished neuroscientist at the Buck Institute for Research on Aging, who discusses he…
In this episode of L…
In this episode of Longevity by Design, hosts Ashley Reaver and Dr. Gil Blander welcome Dr. Julie Andersen, a distinguished neuroscientist at the Buck Institute for Research on Aging, who discusses her groundbreaking work on neurodegenerative diseases, focusing on Parkinson's and Alzheimer's. She explains how the field of geroscience is transforming our understanding of aging, revealing that common underlying processes in various diseases could lead to universal therapeutic approaches.Dr. Andersen dives into the gut-brain connection, highlighting how gut health significantly impacts …
In the latest Ask Me Anything, Ashley and Dr. Blander answer popular questions about optimizing health and longevity. Dr. Blander discusses the rationale behind InsideTracker's shift to a subscription…
In the latest Ask Me…
In the latest Ask Me Anything, Ashley and Dr. Blander answer popular questions about optimizing health and longevity. Dr. Blander discusses the rationale behind InsideTracker's shift to a subscription model, emphasizing the importance of continuous engagement for long-term health improvement. He explains how this model encourages users to maintain their health optimization practices consistently over time, enhancing the overall effectiveness of their health plans.Ashley and Dr. Blander also dive into the recent updates to InsideTracker’s blood work page, which now categorizes biomarkers in…
Listen to this episode of Longevity by Design on Apple Podcasts and Spotify.
Listen to this episo…
Listen to this episode of Longevity by Design on Apple Podcasts and Spotify.
In this episode of Longevity by Design, hosts Ashley Reaver and Dr. Gil Blander welcome Dr. Brianna Stubbs, an expert in exogenous ketone metabolism. Dr. Stubbs shares her journey from being a competi…
In this episode of L…
In this episode of Longevity by Design, hosts Ashley Reaver and Dr. Gil Blander welcome Dr. Brianna Stubbs, an expert in exogenous ketone metabolism. Dr. Stubbs shares her journey from being a competitive rower to becoming a scientist. She dives into her research on ketone biology and its implications for health and aging.Dr. Stubbs discusses the science behind ketones, explaining how they serve as an alternative fuel for the brain and body, particularly during periods of low carbohydrate intake. She highlights the potential benefits of ketones for cognitive function and heart health, noting t…
As you may have heard, male fertility is on the decline. Sperm counts today are 58% lower than they were a century ago. In response, The World Health Organization keeps reducing the definition of "…
As you may have hear…
As you may have heard, male fertility is on the decline. Sperm counts today are 58% lower than they were a century ago. In response, The World Health Organization keeps reducing the definition of "normal." It’s gone down four times since 1980. If this concerns you, it may be because you’ve considered becoming a dad. Most men think about sperm health primarily in the context of having children. But there’s another reason to be concerned. As it turns out, sperm is a sign of your overall health and potential longevity. Simply put, healthy sperm signals a longer, healthier life.�…
You might think drugs like Ozempic, Mounjaro, and Wegovy can do no harm. After all, pundits often describe them as “miracle” weight-loss drugs. So let’s set the record straight. Glucagon-lik…
You might think drug…
You might think drugs like Ozempic, Mounjaro, and Wegovy can do no harm. After all, pundits often describe them as “miracle” weight-loss drugs. So let’s set the record straight. Glucagon-like peptide 1 receptor agonists, or GLP-1s, are complex molecules with complex outcomes. As with other drugs, some of the effects are desirable, and some are not. In the case of GLP-1s, the benefits—primarily weight loss and better metabolic health—can greatly outweigh the costs. But if you want to ensure that’s true for you, you’ll want to manage the side effects as best as you can. I…
It’s rare for a medication to dominate headlines. But GLP-1 receptor agonists have done just that. Going by names like Ozempic, Wegovy, and Mounjaro, GLP-1s have captured the world’s imaginatio…
It’s rare for a me…
It’s rare for a medication to dominate headlines. But GLP-1 receptor agonists have done just that. Going by names like Ozempic, Wegovy, and Mounjaro, GLP-1s have captured the world’s imagination and redefined how we think about weight. If you’ve struggled with obesity, you may see these injections as the first ray of hope to come along in your lifetime. And you’re not alone. To date, one in eight adults have used GLP-1s, according to a recent KFF poll. [1] The data is clear that these medications do a lot of good. But as with any drug, there are the effects you want, and the one…
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