In this episode of the Aging Well podcast, we explore the crucial role that sleep and circadian rhythms play in maintaining cognitive health, particularly in relation to Alzheimer's disease, dementia, and age-related cognitive decline. We discuss the importance of sleep hygiene, the impact of sleep quality on brain health, and how disruptions in circadian rhythms can accelerate neurodegenerative diseases. The conversation also touches on sleep architecture, mechanisms linking sleep disruptions to neurodegeneration, and practical strategies to improve sleep and circadian alignment. Additionally, we review the benefits and drawbacks of sleep aids and the importance of personalized approaches to optimizing sleep for healthy aging.

Alzheimer's Amyloid Tied to Circadian Disruption Earlier in Life
Clinical Challenges: Alzheimer's and Sleep May Share Bidirectional Links
Association of Sleep Duration in Middle and Old Age with Incidence of Dementia
Daytime Napping and Alzheimer’s Dementia: A Potential Bidirectional Relationship
Sleep, 24-hr Activity Rythyms, and Subsequent Amyloid-b Pathology
Subcortical Neuronal Correlates of Sleep in Neurodegenerative Diseases

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Jeff Armstrong W. Jeffrey Armstrong, Ph.D.

Jeff Armstrong is a professor of Exercise Science (Ph.D., Exercise Physiology) at Western Oregon University and host of the Aging Well Podcast. He authored the textbook, 'Pathophysiology & Exercise' (Kendall-Hunt) and teaches a breath of courses from this to Advanced Programming for Sport & Fitness. He is passionate about longevity, health, improving/maintaining performance (Spiritually, Physically, Intellectually, Emotionally, and Socially--what he refers to as "well-centered fitness") across the lifespan, and aging well.