Globally, 2.3 million women are diagnosed with breast Cancer every year, according to the World Health Organization. It is also the most common cancer among women worldwide. While early detection and improved treatments have contributed to better survival rates, breast cancer remains a significant health challenge. According to the American Cancer Society (ACS), about 1 in 8 women in the U.S. will develop breast cancer at some point in their lifetime.

The risk escalates with age, with women over the age of 50 accounting for approximately 80% of all breast cancer diagnoses. The median age for diagnosis in the U.S. is around 62 years, although new data shows the number of cases among women under 50 years of age is rising. Despite this concerning news – which researchers are working to understand – the same report showed that the number of deaths from breast cancer declined by 44% between 1989 and 2022.  

The state of the science

Advances in breast cancer research are providing new hope for both prevention and treatment. Several recent studies focus on precision medicine, targeting breast cancer treatments based on the unique genetic makeup of the tumor. A few noteworthy developments include:

• Targeted therapies: Drugs like trastuzumab (Herceptin) and pertuzumab (Perjeta) have revolutionized the treatment of HER2-positive breast cancer by targeting specific proteins that promote cancer Growth. Researchers are also investigating novel drugs that target triple-negative breast cancer, a more aggressive form that has fewer treatment options.
• Immunotherapy: Recent trials show that immunotherapy, which enhances the body’s immune response to cancer, holds promise for breast cancer patients, especially when combined with chemotherapy. Pembrolizumab (Keytruda), for example, has been approved for treating certain types of breast cancer.
• Early detection and prevention: Genetic testing for mutations in the BRCA1 and BRCA2 genes, which increase breast cancer risk, is becoming more accessible. In addition, researchers are exploring the potential of liquid biopsies, a non-invasive blood test that could detect cancer early by identifying circulating tumor DNA.

These innovations are improving the outlook for breast cancer patients, but prevention remains key. Fortunately, there are Lifestyle choices that can help reduce breast cancer risk.

As with many other conditions, Diet plays a significant role in breast cancer prevention and management. While, of course, no single food can guarantee protection, healthy dietary patterns may reduce the risk. It’s no surprise that the foods on this list are also considered “longevity foods”, which we reported on here. Even more reason to make a place for them on your plate!

Foods to help with the fight

1. Cruciferous Vegetables: Broccoli, cauliflower, and kale are rich in glucosinolates, compounds that have been shown to reduce breast cancer risk by aiding in the detoxification of potential carcinogens.
2. Berries: Blueberries, strawberries, and raspberries are high in antioxidants, which help protect cells from DNA damage that can lead to cancer.
3. Fatty Fish: Salmon, mackerel, and sardines are excellent sources of omega-3 fatty acids, which have been linked to lower breast cancer risk due to their anti-inflammatory properties.
4. Flaxseeds: High in lignans, flaxseeds may help lower estrogen levels and reduce the risk of hormone-dependent breast cancers.
5. Leafy Greens: Spinach, kale, and other dark leafy greens are packed with vitamins and antioxidants that help protect against cancer.

Foods to avoid (or limit):

Regular alcohol consumption is a risk factor for breast cancer. Even moderate drinking (about one drink per day) has been associated with an increased risk.

High intake of red meat, particularly processed meats like bacon and sausages, has also been linked to increased cancer risk. These meats can contain carcinogenic compounds, especially when cooked at high temperatures. Sugary foods and refined carbohydrates can lead to weight gain and insulin resistance, which in turn are risk factors for breast cancer.

Some studies suggest that high-fat dairy products, such as butter and whole milk, may increase breast cancer risk due to their high levels of estrogen and other hormones.

Other things you can do

Beyond diet, these lifestyle factors can help to reduce breast cancer risk and boost overall health:

1. Stay active: Regular physical activity helps maintain a healthy weight, reduces inflammation, and lowers estrogen levels, all of which are protective against breast cancer. The ACS recommends at least 150 minutes of moderate Exercise or 75 minutes of vigorous exercise each week. Not only could exercise help to prevent breast cancer, but it may protect against many other conditions, as well. Read our story on the big benefits regular exercise brings to longevity.
2. Maintain a healthy weight: Obesity, particularly after Menopause, is linked to an increased risk of breast cancer.
3. Limit Hormone Replacement Therapy (HRT): Long-term use of hormone replacement therapy for menopausal symptoms has been associated with an increased risk of breast cancer. Talk to your doctor about the benefits and risks of HRT.
4. Quit smoking: Smoking has been linked to a higher risk of breast cancer, particularly in younger, premenopausal women. Quitting smoking can improve overall health and reduce cancer risk.

The bottom line

While breast cancer risk, like with many other cancers, increases with age, there are many ways to reduce that risk. From new targeted therapies and genetic testing to dietary and lifestyle changes, advances in breast cancer prevention and treatment offer more hope than ever.

More on preventing cancer:

Foods that help to fight cancer

A blood test that screens for multiple cancers at once promises to boost early detection

Nearly half of all US cancer deaths may be prevented by making these 6 lifestyle changes

The big benefits of small fish for health and longevity

Coffee a “mini-Mediterranean diet” with many benefits

Content on this site is for informational purposes only and is not a substitute for professional medical advice. Always check with your qualified healthcare providers with any questions or concerns regarding a medical condition.

David Cravit SuperAging News

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