1. 289 - An Outside the box Alzheimer's Treatment? How Biovie is Modulating Inflammation Alzheimer's Caregivers 41:05

289 - An Outside The Box Alzheimer'S Treatment? How Biovie Is Modulating Inflammation &Raquo; Sarah Horz

The Alzheimer’s Association says that “we’re in an era of treatments now,” which is excellent, but these treatments aren’t suitable for everyone with Alzheimer’s. That’s why I’m excited that I have been approached by start-ups that are looking at treatments from a different angle. We’ve got InmuneBio targeting the immune cells in the brain, and today, I’m speaking with Sara Holt of BioVie, a clinical-stage company developing a novel approach to treating Alzheimer’s disease.

In this episode, you’ll learn about Biovie’s work and how it could affect us in the near future. You’ll hear Sarah’s story first, which led her to work with them. This is an inspirational and informative episode that is very fascinating.

BioVie believes targeting neuroinflammation could be the key to finding an effective Alzheimer’s therapy. Their lead compound, NE3107, aims to modulate inflammation and improve energy metabolism in the brain. NE3107 is now in Phase 3 clinical trials, with results expected in late 2023. On today’s show, we’ll discuss BioVie’s unique approach, how NE3107 works, and the progress of its clinical program.

We’ll also examine the evidence linking inflammation to Alzheimer’s progression and why some experts believe this represents an untapped target for drug development. With over 6 million Americans living with Alzheimer’s and only recent potential treatments approved, BioVie’s research offers additional hope.

Join us as we explore whether NE3107 could pave the way to the first new class of Alzheimer’s drugs in years. Learn more at BioViePharma.com.

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After helping care for her grandmother who had vascular dementia, Jennifer realized her Mother was showing signs of early onset Alzheimer’s. After the death of her father in 2017 Jennifer went searching for answers to many of the common questions and Alzheimer’s caregiver faces. Being a busy entrepreneur Jennifer realized that a podcast would be the easiest way to learn more about caregiving while completing other tasks.

Sadly, in late 2017 she only found one and it didn’t quite address what she was looking for, so she did the next best thing, and started her own. The Fading Memories podcast is now in it’s fourth year and despite the death of her Mom in March 2020, Jennifer is still talking to caregivers and still learning how to be an excellent caregiver. On the podcast she discusses caregiving, brain health, self-care and how to age well.